The project focuses on five Research Nodes. Three "vertical" Research Nodes address the following topics: Emerging and re-emerging viral threats (with a focus on respiratory viruses and zoonoses); Arthropod vectors and vector-borne pathogens; Diseases caused by bacteria and fungi resistant to multiple antibiotics (AMR, with a focus on molecular mechanisms of multi-antibiotic resistance). Two transversal Research Nodes interact bidirectionally with the basic and translational activities of the three Research Nodes described above: Integrated epidemiology in a "One Health" perspective (human, animal and environment), monitoring and mathematical models; Development of new therapeutic strategies (identification of molecular targets, generation of libraries of molecules for drug discovery approaches, testing of possible effective candidates and their optimization).
| Partners: | Università degli Studi di Pavia (UNIPV); Università degli Studi di Padova (UNIPD);Università degli Studi di Catania (UNICT); Istituto Superiore di Sanità (ISS); Università degli Studi di Milano (UNIMI); Università degli Studi di Roma |
| Type: | Internazionale - PNRR-partnenariati esteri |
| Start: | 01/11/2022 |
| End: | 31-10-2025 |
| Amount: | 114.500.000 ? |
| Leader: | NO |
| Referent: | VINCENZINA FUSCO |